Difference between revisions of "NtdC"
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* '''Operon:''' ''[[ntdA]]-[[ntdB]]-[[ntdC]]-[[glcP]]'' {{PubMed|17056753}} | * '''Operon:''' ''[[ntdA]]-[[ntdB]]-[[ntdC]]-[[glcP]]'' {{PubMed|17056753}} | ||
| − | * '''[ | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ntdC_1126400_1127452_-1 ntdC] {{PubMed|22383849}} |
| + | |||
| + | * '''Sigma factor:''' [[SigA]] {{PubMed|14612444}} | ||
* '''Regulation:''' induced by 3,3'-neotrehalosadiamine ([[NtdR]]) {{PubMed|14612444}} | * '''Regulation:''' induced by 3,3'-neotrehalosadiamine ([[NtdR]]) {{PubMed|14612444}} | ||
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* '''Regulatory mechanism:''' [[NtdR]]: positive regulator {{PubMed|14612444}} | * '''Regulatory mechanism:''' [[NtdR]]: positive regulator {{PubMed|14612444}} | ||
| − | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = | ||
Revision as of 17:20, 12 April 2012
- Description: synthesis of the antibiotic neotrehalosadiamine
| Gene name | ntdC |
| Synonyms | yhjJ |
| Essential | no |
| Product | unknown |
| Function | synthesis of the antibiotic neotrehalosadiamine |
| MW, pI | 39 kDa, 6.227 |
| Gene length, protein length | 1050 bp, 350 aa |
| Immediate neighbours | glcP, ntdB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU10530
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: gfo/idh/mocA family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O07564
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original publications
Takashi Inaoka, Takenori Satomura, Yasutaro Fujita, Kozo Ochi
Novel gene regulation mediated by overproduction of secondary metabolite neotrehalosadiamine in Bacillus subtilis.
FEMS Microbiol Lett: 2009, 291(2);151-6
[PubMed:19087206]
[WorldCat.org]
[DOI]
(I p)
Takashi Inaoka, Kozo Ochi
Glucose uptake pathway-specific regulation of synthesis of neotrehalosadiamine, a novel autoinducer produced in Bacillus subtilis.
J Bacteriol: 2007, 189(1);65-75
[PubMed:17056753]
[WorldCat.org]
[DOI]
(P p)
Takashi Inaoka, Kosaku Takahashi, Hiroshi Yada, Mitsuru Yoshida, Kozo Ochi
RNA polymerase mutation activates the production of a dormant antibiotic 3,3'-neotrehalosadiamine via an autoinduction mechanism in Bacillus subtilis.
J Biol Chem: 2004, 279(5);3885-92
[PubMed:14612444]
[WorldCat.org]
[DOI]
(P p)
