Difference between revisions of "TsaD"

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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=gcp_643258_644298_1 gcp] {{PubMed|22383849}}
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=Biological materials =
 
=Biological materials =

Revision as of 15:17, 12 April 2012

  • Description: there are two annotations for the corresponding E. coli protein: O-sialoglycoprotein endopeptidase, and required for threonyl carbamoyl adenosine (t6A) modification of tRNAs that pair with ANN codons in mRNA (together with YwlC), universally conserved protein

Gene name gcp
Synonyms ydiE
Essential yes PubMed
Product O-sialoglycoprotein endopeptidase (putative)
Function tRNA modification
Interactions involving this protein in SubtInteract: Gcp
MW, pI 36 kDa, 5.016
Gene length, protein length 1038 bp, 346 aa
Immediate neighbours ydiD, ydiF
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
Gcp context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

translation, essential genes, universally conserved proteins, poorly characterized/ putative enzymes

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU05940

Phenotypes of a mutant

essential PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs PubMed
    • conserved glycopeptidase that may be directly involved in the metabolism of glycated proteins PubMed
  • Protein family: peptidase M22 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

universally conserved protein

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Publications on the corresponding E. coli protein, YgjD