Difference between revisions of "SplB"
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=== Additional information=== | === Additional information=== | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
| − | * '''Catalyzed reaction/ biological activity:''' 5-thyminyl-5,6-dihydrothymine (in DNA) = 2 thymine residues (in DNA) (according to Swiss-Prot) | + | * '''Catalyzed reaction/ biological activity:''' |
| + | ** repairs a special thymine dimer (5-thyminyl-5,6-dihydrothymine), which is commonly called spore photoproduct at the early germination phase | ||
| + | ** 5-thyminyl-5,6-dihydrothymine (in DNA) = 2 thymine residues (in DNA) (according to Swiss-Prot) | ||
* '''Protein family:''' | * '''Protein family:''' | ||
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* '''Modification:''' | * '''Modification:''' | ||
| − | * '''Cofactor(s):''' contains | + | * '''Cofactor(s):''' |
| + | ** contains a [4Fe-4S] cluster | ||
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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=References= | =References= | ||
| − | <pubmed> 15699190,8021181 21671623 </pubmed> | + | <pubmed> 15699190,8021181 21671623 22197590</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:54, 27 December 2011
- Description: spore photoproduct lyase
| Gene name | splB |
| Synonyms | spl |
| Essential | no |
| Product | spore photoproduct lyase |
| Function | protection of spore DNA against photodamage |
| MW, pI | 39 kDa, 8.524 |
| Gene length, protein length | 1026 bp, 342 aa |
| Immediate neighbours | splA, ykwB |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
DNA repair/ recombination, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13930
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- repairs a special thymine dimer (5-thyminyl-5,6-dihydrothymine), which is commonly called spore photoproduct at the early germination phase
- 5-thyminyl-5,6-dihydrothymine (in DNA) = 2 thymine residues (in DNA) (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- contains a [4Fe-4S] cluster
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P37956
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
