RbsK

• Description: ribokinase
  
  

Gene name	rbsK
Synonyms
Essential	no
Product	ribokinase
Function	ribose utilization
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	30 kDa, 4.61
Gene length, protein length	879 bp, 293 aa
Immediate neighbours	rbsR, rbsD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

AbrB regulon, CcpA regulon

The gene

Basic information

• Locus tag: BSU35920

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + D-ribose = ADP + D-ribose 5-phosphate (according to Swiss-Prot)

• Protein family: carbohydrate kinase pfkB family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P36945

• KEGG entry: [3]

• E.C. number: 2.7.1.15

Expression and regulation

• Operon: rbsR-rbsK-rbsD-rbsA-rbsC-rbsB PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • repressed by glucose (CcpA) PubMed
  • expressed upon transition into the stationary phase (AbrB) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • AbrB: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: