Difference between revisions of "BslA"

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* '''Description:''' required for complex colony architecture<br/><br/>
+
* '''Description:''' required for complex colony architecture, facilitates biofilm matrix assembly<br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || unknown
+
|style="background:#ABCDEF;" align="center"| '''Product''' || cell wall protein
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"|'''Function''' || pellicle formation
 
|style="background:#ABCDEF;" align="center"|'''Function''' || pellicle formation
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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* reduced colony complexity {{PubMed|21742882}}
  
 
=== Database entries ===
 
=== Database entries ===
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Interactions:'''
 
* '''Interactions:'''
  
* '''Localization:''' membrane (according to Swiss-Prot),  extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed]
+
* '''Localization:'''  
 +
** extracellular (signal peptide) [http://www.ncbi.nlm.nih.gov/pubmed/18957862 PubMed]
 +
** cell wall {{PubMed|21742882}}
  
 
=== Database entries ===
 
=== Database entries ===
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* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[DegU]]-P: transcription activation {{PubMed|18978066}}
+
** [[DegU]]-P: transcription activation {{PubMed|18978066}}, this might be indirect {{PubMed|21742882}}
 
** [[AbrB]]: transcription repression {{PubMed|18978066}}
 
** [[AbrB]]: transcription repression {{PubMed|18978066}}
  
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=References=
 
=References=
<pubmed> 18978066 18957862, 17850253 21097620 </pubmed>
+
<pubmed> 18978066 18957862, 17850253 21097620 21742882 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:25, 12 July 2011

  • Description: required for complex colony architecture, facilitates biofilm matrix assembly

Gene name yuaB
Synonyms
Essential no
Product cell wall protein
Function pellicle formation
MW, pI 19 kDa, 9.987
Gene length, protein length 543 bp, 181 aa
Immediate neighbours yuaC, ktrA
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YuaB context.gif
This image was kindly provided by SubtiList



Categories containing this gene/protein

biofilm formation

This gene is a member of the following regulons

AbrB regulon, DegU regulon

The gene

Basic information

  • Locus tag: BSU31080

Phenotypes of a mutant

  • reduced colony complexity PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulation:
    • expression is down-regulated in a rok mutant (indirect effect) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References