SdpA

• Description: maybe involved in cannibalism of siblings
  
  

Gene name	sdpA
Synonyms	yvaW
Essential	no
Product	unknown
Function	unknown
MW, pI	18 kDa, 9.766
Gene length, protein length	474 bp, 158 aa
Immediate neighbours	yvaV, sdpB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU33750

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Categories containing this gene/protein

toxins, antitoxins and immunity against toxins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34889

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: sdpA-sdpB-sdpC PubMed

• Sigma factor:

• Regulation: repressed by glucose (8-fold) PubMed
  • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • repressed by Rok PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • Spo0A: transcription activation PubMed
  • Rok: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

José Eduardo González-Pastor
Cannibalism: a social behavior in sporulating Bacillus subtilis.
FEMS Microbiol Rev: 2011, 35(3);415-24
[PubMed:20955377] [WorldCat.org] [DOI] (I p)