Difference between revisions of "PhrE"

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(Expression and regulation)
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** [[ComA]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/10629174 PubMed]
 
** [[ComA]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/10629174 PubMed]
  
* '''Regulatory mechanism:''' [[CcpA]]: transcription repression  
+
* '''Regulatory mechanism:'''  
 +
** [[CcpA]]: transcription repression  
 
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
 
** [[CodY]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/12618455 PubMed]
 +
** [[AbrB]]: transcription repression {{PubMed|20817675}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
  
<pubmed>12618455,12850135,11466295,10629174 </pubmed>
+
<pubmed>12618455,12850135,11466295,10629174 20817675</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 20:04, 15 September 2010

Gene name phrE
Synonyms
Essential no
Product phosphatase (RapE) regulator
Function control of sporulation initiation
Function and regulation of this protein in SubtiPathways:
Phosphorelay
MW, pI 4 kDa, 8.863
Gene length, protein length 132 bp, 44 aa
Immediate neighbours rapE, yqzI
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PhrE context.gif
This image was kindly provided by SubtiList







The gene

Basic information

  • Locus tag: BSU25840

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: repressed by glucose (10-fold) (CcpA) PubMed
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
    • ComA: transcription activation PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References