Difference between revisions of "SpoIIGA"

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* '''Description:''' Pro-SigE protease <br/><br/>
+
* '''Description:''' Pro-[[SigE]] protease <br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || Pro-SigE protease
+
|style="background:#ABCDEF;" align="center"| '''Product''' || Pro-[[SigE]] protease
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || maturation of SigE
+
|style="background:#ABCDEF;" align="center"|'''Function''' || maturation of [[SigE]]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34 kDa, 8.552   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 34 kDa, 8.552   
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=Expression and regulation=
 
=Expression and regulation=
  
* '''Operon:''' ''[[spoIIGA]]-[[sigE]]-[[sigG]]''
+
* '''Operon:''' ''[[spoIIGA]]-[[sigE]]-[[sigG]]'' {{PubMed|1902213}}
  
* '''[[Sigma factor]]:''' [[SigA]]
+
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2512576}}
  
* '''Regulation:''' expressed early during sporulation ([[Spo0A]])
+
* '''Regulation:'''  
 
** expressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]
 
** expressed under conditions that trigger sporulation ([[Spo0A]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]
  
* '''Regulatory mechanism:''' activated by [[Spo0A]], repression by [[SinR]]
+
* '''Regulatory mechanism:'''  
 +
** repression by [[SinR]]
 
** [[Spo0A]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]
 
** [[Spo0A]]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/8288522,15687200 PubMed]
  

Revision as of 17:08, 10 October 2009

  • Description: Pro-SigE protease

Gene name spoIIGA
Synonyms
Essential no
Product Pro-SigE protease
Function maturation of SigE
MW, pI 34 kDa, 8.552
Gene length, protein length 927 bp, 309 aa
Immediate neighbours bpr, sigE
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SpoIIGA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU15310

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: peptidase U4 family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions that trigger sporulation (Spo0A) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References