tagV

tagV
168

phosphotransferase, attaches teichoic acid, teichuronic acid, or acidic capsular polysaccharide to cell wall peptidoglycan via phosphodiester linkage to N-acteylmuramic acid

Locus
BSU_35520
Molecular weight
43.05 kDa
Isoelectric point
9.14
Protein length
391 aaSequenceBlast
Gene length
1176 bpSequenceBlast
Function
transfer of anionic cell wall polymers from lipid-linked precursors to peptidoglycan
Product
phosphotransferase, responsible for attachment of anionic polymers to peptidoglycan
Essential
no
Synonyms
tagV, yvhJ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1316 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,647,406 → 3,648,581
Phenotypes of a mutant
a ''tagV mutant has no phenoype, the triple tagT tagU tagV'' mutant is unable to grow under normal conditions PubMed
poor growth of a bcrC tagV double mutant PubMed
inactivation suppresses the essentiality of mbl PubMed
The protein
Protein family
LytR/CpsA/Psr (LCP) family (with TagU and TagT, according to UniProt) PubMed
Cofactors
Mg2+ PubMed
Structure
6UF3 (PDB) (aa 72-332) PubMed
3NXH (PDB)
P96499 (AlphaFold)
Paralogous protein(s)
TagU, TagT
Localization
cytoplasmic membrane (with extracytoplasmic catalaytic domain) PubMed
Expression and Regulation
Operons
Genes
yvyE-tagV
Description
PubMed
Regulation
repressed under conditions that trigger sporulation (Spo0A) PubMed
Regulatory mechanism
Spo0A: repression, PubMed, in spo0A regulon
Open in new tab

yvyE→tagV

2025-03-16 13:53:30

ghost

97

434d5c1034a945aaa3ecc1561c073981d68a60ce

06E62DFCE6F5AF65909104B2BE1D0FEF606B7CDC

Biological materials
Mutant
MGNA-A344 (yvhJ::erm), available at the NBRP B. subtilis, Japan
BKE35520 (ΔtagV::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACGCACTCTAACGCGTTCAG,  downstream forward: _UP4_TAAAAAATGCCCGGTCCTTT
BKK35520 (ΔtagV::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_ACGCACTCTAACGCGTTCAG,  downstream forward: _UP4_TAAAAAATGCCCGGTCCTTT
References
Reviews
Loading
Original Publications
Loading

E244A5ABB2FBD4FC3880F0DB700BD935991AE6DD

Page visits: 3992

Time of last update: 2025-04-05 02:03:36

Author of last update: Jstuelk