yfjA

yfjA
168

putative chaperone, essential for the toxic activity of the YfjB-YfjC toxin

Locus
BSU_08170
Molecular weight
11.89 kDa
Isoelectric point
4.86
Protein length
104 aaSequenceBlast
Gene length
315 bpSequenceBlast
Function
unknown
Product
putative chaperone support the YfjB-YfjC toxin
Essential
no
Synonyms
yfjA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG4842 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
889,372  889,686
The protein
Protein family
WXG100 family (with YukE, according to UniProt) (pfam06013) PubMed
Structure
2VRZ (PDB) (from Staphylococcus aureus, 21% identity) PubMed
O31558 (AlphaFold)
Localization
secreted, by the type VII protein secretion system YukD-EssB-YukB-YueB-YueC PubMed
Expression and Regulation
Operons
Genes
yfjA-yfjB-yfjC-yfjD-yfjE-yfjF
Description
PubMed
Expression
expressed in the subset of cells that undergoes sporulation PubMed
Regulatory mechanism
DegU: transcription activation, PubMed, in degU regulon
Open in new tab

yfjA→yfjF

2025-03-17 19:33:19

Jstuelk

96

AC055875C4E039DF08AE568C825D5A55BFDF9629

5CDE782AC458249C2230482A8333E5FD084FF0F2

Biological materials
Mutant
MGNA-C288 (yfjA::erm), available at the NBRP B. subtilis, Japan
BKE08170 (yfjA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACTTTTGTCCCCTGCCTT,  downstream forward: _UP4_CATAAACTCGGGAGGTGAAC
BKK08170 (yfjA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAACTTTTGTCCCCTGCCTT,  downstream forward: _UP4_CATAAACTCGGGAGGTGAAC
References
Loading

A177DF098115F85F23A1D42EFB07D294B515830F

Page visits: 2383

Time of last update: 2025-04-01 17:45:26

Author of last update: Jstuelk