gmuD

gmuD
168

phospho-beta-mannosidase

Locus
BSU_05840
Molecular weight
54.17 kDa
Isoelectric point
5.73
Protein length
465 aaSequenceBlast
Gene length
1398 bpSequenceBlast
Function
glucomannan utilization
Product
phospho-beta-mannosidase
Essential
no
Synonyms
gmuD, ydhP
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2723 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
628,630 → 630,027
The protein
Catalyzed reaction/ biological activity
6-phospho-β-D-glucosyl-(1→4)-D-glucose + H2O --> D-glucose + D-glucose 6-phosphate (according to UniProt)
Protein family
glycosyl hydrolase 1 family (according to UniProt)
Structure
4B3K (PDB) (from Streptococcus pyogenes, 50% identity) PubMed
O05508 (AlphaFold)
Expression and Regulation
Operons
Genes
gmuB-gmuA-gmuC-gmuD-gmuR-gmuE-gmuF-gmuG
Description
PubMed
Regulation
induced by cellobiose (GmuR) PubMed
Regulatory mechanism
GmuR: repression, PubMed, in gmuR regulon
CcpA: repression, PubMed, in ccpA regulon
AbrB: activation, PubMed, in abrB regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

gmuB→gmuG

2025-03-16 15:57:23

Jstuelk

109

1716709ba10a9af523abc0d89eb44ea784dd12d9

42FBC6CD7712CC913DB98C4B417CB4A13C8FAE20

Biological materials
Mutant
MGNA-C191 (ydhP::erm), available at the NBRP B. subtilis, Japan
BKE05840 (ΔgmuD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGCCAAGTCTCTCTCCCCTT,  downstream forward: _UP4_TAGATTTTCCTAAAGGTCAA
BKK05840 (ΔgmuD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGCCAAGTCTCTCTCCCCTT,  downstream forward: _UP4_TAGATTTTCCTAAAGGTCAA
References
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Time of last update: 2025-04-02 20:29:07

Author of last update: Jstuelk