shfA

shfA
168

sporulation heterogeneity factor Antidote, required for sporulation at a late stage

Locus
BSU_00610
Molecular weight
24.95 kDa
Isoelectric point
10.74
Protein length
211 aaSequenceBlast
Gene length
636 bpSequenceBlast
Function
control of sporulation entry in neighbor cells
Product
sporulation heterogeneity factor Antidote
Essential
no
Synonyms
yabQ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG5869 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
68,515  69,150
Phenotypes of a mutant
inactivation of shfA reduces sporulation efficiency to 0.1% that of wild type cells PubMed, this can be suppressed by inactivation of shfP PubMed
The protein
Structure
P37559 (AlphaFold)
Localization
forespore outer membrane PubMed
Expression and Regulation
Operons
Genes
yabM-yabN-rqcP-yabP-shfA-divIC-yabR
Description
PubMed
Regulation
expressed during sporulation (SigE) PubMed
Sigma factors
SigM: sigma factor, PubMed, in sigM regulon
SigE: sigma factor, PubMed, in sigE regulon
SigW: sigma factor, PubMed, in sigW regulon
SigD: sigma factor, PubMed, in sigD regulon
SigX: sigma factor, PubMed, in sigX regulon
Open in new tab

yabM→yabR

2025-03-17 17:29:55

Jstuelk

117

93952be38722510f984794e138450cd80a9f7d48

0CF3909333400A3BFE18E32016883124FFC3D75B

Genes
yabP-shfA-divIC-yabR
Description
PubMed
Regulation
expressed during sporulation (SigE) PubMed
Additional information
there are about 50,000 molecules of DivIC per cell PubMed
Open in new tab

yabP→yabR

2025-03-16 19:27:44

ghost

89

adf8aab8f33a2b64c2ab3f1426fc15c0793898c5

4D8628337CAF16F8F83A7EEB7090199FCE86D5A2

Biological materials
Mutant
MGNA-B918 (yabQ::erm), available at the NBRP B. subtilis, Japan
BKE00610 (shfA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGTATAGAATTGTGTCGTCA,  downstream forward: _UP4_AGATGAAAGGAGGACCGTCT
BKK00610 (shfA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGTATAGAATTGTGTCGTCA,  downstream forward: _UP4_AGATGAAAGGAGGACCGTCT
References
Loading

4DEDB27C0162409571AB4A1BB17CFE400764AE45

Page visits: 4503

Time of last update: 2025-03-31 13:18:31

Author of last update: Jstuelk