uvrX

uvrX
168

UV-damage repair protein

Locus
BSU_21500
Molecular weight
46.57 kDa
Isoelectric point
9.63
Protein length
416 aaSequenceBlast
Gene length
1251 bpSequenceBlast
Function
DNA repair after UV damage
Product
UV-damage repair protein
Essential
no
Synonyms
uvrX, yolE
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0389 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,270,407 → 2,271,657
Phenotypes of a mutant
reduced formation of rpsB or rpsE suppressor mutants after mitomycin treatment PubMed
The protein
Protein family
DNA polymerase type-Y family (according to UniProt)
Domains
UmuC domain (aa 12-196) (according to UniProt)
Structure
O31990 (AlphaFold)
Paralogous protein(s)
PolY1, PolY2
Expression and Regulation
Operons
Genes
yolD-uvrX
Description
PubMed
Regulation
induced by DNA damage (LexA) PubMed
Regulatory mechanism
LexA: repression, PubMed, in lexA regulon
Open in new tab

yolD→uvrX

2025-02-26 23:03:33

ghost

76

75abea45b56916be6c2da15dea6c26c9903e3f54

4B3A377D69E222FC756C7EB6DE6DAB9836226A58

Biological materials
Mutant
BKE21500 (ΔuvrX::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AATCAATCATTGTATGTAAC,  downstream forward: _UP4_TAAGATAAATTTAAACTTAT
BKK21500 (ΔuvrX::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AATCAATCATTGTATGTAAC,  downstream forward: _UP4_TAAGATAAATTTAAACTTAT
References
Loading

BE8D5E038C0FD748C0F9C3F18DCA601BFFE8EA52

Page visits: 4202

Time of last update: 2025-04-03 10:05:01

Author of last update: Jstuelk