pel

pel
168

pectate lyase C

Locus
BSU_07560
Molecular weight
45.34 kDa
Isoelectric point
8.42
Protein length
420 aaSequenceBlast
Gene length
1263 bpSequenceBlast
Function
degradation of polygalacturonic acid
Product
pectate lyase C
Essential
no
E.C.
4.2.2.2
Synonyms
pel
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3866 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
827,993  829,255
The protein
Catalyzed reaction/ biological activity
Eliminative cleavage of (14)-alpha-D-galacturonan to give oligosaccharides with 4-deoxy-alpha-D-galact-4-enuronosyl groups at their non-reducing ends (according to UniProt)
Protein family
lyase 1 family (according to UniProt)
Structure
2O1D (PDB) (bound to trisaccharide),  1BN8 (PDB), 5X2I (PDB)
P39116 (AlphaFold)
Localization
extracellular (signal peptide), major constituent of the secretome PubMed
Expression and Regulation
Operons
Genes
pel
Description
PubMed
Regulation
expressed at high cell density (ComA) PubMed
Regulatory mechanism
CcpA: repression, in ccpA regulon
TnrA: repression, PubMed, in tnrA regulon
ComA: activation, (ComA) PubMed, in comA regulon
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pel

2025-03-16 02:54:35

ghost

72

76400bab62705b87994cb03faede33a889fce495

10714B5E27307FB494D6E1512AD3F8A90541AB1B

Biological materials
Mutant
MGNA-C248 (pel::erm), available at the NBRP B. subtilis, Japan
BKE07560 (pel::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCACTATGTACCCCCAT,  downstream forward: _UP4_TAAGAAAGTGAAAAACACAA
BKK07560 (pel::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATCCACTATGTACCCCCAT,  downstream forward: _UP4_TAAGAAAGTGAAAAACACAA
References
Reviews
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Original Publications
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60595234B02D673E860B364FE8A3C83D2CC68CB2

Page visits: 3263

Time of last update: 2025-04-01 18:42:36

Author of last update: Jstuelk