oxdC

oxdC
168

oxalate decarboxylase

Locus
BSU_33240
Molecular weight
43.41 kDa
Isoelectric point
5.1
Protein length
385 aaSequenceBlast
Gene length
1158 bpSequenceBlast
Function
unknown
Product
oxalate decarboxylase
Essential
no
E.C.
4.1.1.2
Synonyms
oxdC, yvrK
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2140 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,410,466  3,411,623
The protein
Catalyzed reaction/ biological activity
H+ + oxalate --> CO2 + formate (according to UniProt)
Cofactors
requires two Mn(II) centers for activity PubMed
Structure
1L3J (PDB) PubMed
O34714 (AlphaFold)
Modification
phosphorylated on Arg-12 PubMed
Paralogous protein(s)
OxdD
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
oxdC-rsiO
Description
PubMed
Regulation
induced by acidic growth conditions PubMed
Sigma factors
SigO: sigma factor, PubMed, in sigO regulon
RsoA: sigma factor, in rsoA regulon
Open in new tab

oxdC→rsiO

2025-03-14 08:28:20

ghost

82

45fe15923d4d9abe55bc1d08f5e4cf8ec93e3aab

C45787333A7E680B1778F2A70AF5C84FB28484FA

Biological materials
Mutant
MGNA-B053 (yvrK::erm), available at the NBRP B. subtilis, Japan
BKE33240 (oxdC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGAAATGTTTCCTCCTTA,  downstream forward: _UP4_TAAAAGACTTGCGGCTTGCA
BKK33240 (oxdC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGAAATGTTTCCTCCTTA,  downstream forward: _UP4_TAAAAGACTTGCGGCTTGCA
Labs working on this gene/protein
John Helmann, Cornell University, USA Homepage
References
Reviews
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Original Publications
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9793E952C985BA268AC28C907900A03F4E8A3253

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Time of last update: 2025-04-01 14:38:45

Author of last update: Jstuelk