mdtP

mdtP
168

multidrug-efflux transporter

Locus
BSU_32880
Molecular weight
57.78 kDa
Isoelectric point
9.84
Protein length
541 aaSequenceBlast
Gene length
1626 bpSequenceBlast
Function
multidrug resistance
Product
multidrug-efflux transporter
Essential
no
Synonyms
mdtP, yusP
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,374,956  3,376,581
The protein
Protein family
major facilitator superfamily (according to UniProt)
EmrB family (according to UniProt)
Structure
O32182 (AlphaFold)
Localization
cell membrane (according to UniProt),  membrane associated PubMed
Expression and Regulation
Operons
Genes
mdtR-mdtP
Description
PubMed
Regulatory mechanism
MdtR: repression, PubMed, in mdtR regulon
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mdtR→mdtP

2025-03-14 20:23:51

ghost

113

e8ef0633959f1f2e66057727f720be97f7312a4d

F311909F49C8D0FC01C8D2C80963778BC55777F7

Biological materials
Mutant
MGNA-A601 (yusP::erm), available at the NBRP B. subtilis, Japan
BP70 (spc) available in Fabian Commichau's lab
BKE32880 (mdtP::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTGTTTGCCTTCTTTACTCA,  downstream forward: _UP4_TAATAGAGCACCCCGCGGGT
BKK32880 (mdtP::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TTGTTTGCCTTCTTTACTCA,  downstream forward: _UP4_TAATAGAGCACCCCGCGGGT
References
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45C61C1584A851676F15A2249F3F1092863C5AA5

Page visits: 2838

Time of last update: 2025-03-30 14:43:07

Author of last update: Melvin.boenninger