bsdC

bsdC
168

phenolic acid decarboxylase

Locus
BSU_03640
Molecular weight
52.86 kDa
Isoelectric point
5.12
Protein length
473 aaSequenceBlast
Gene length
1422 bpSequenceBlast
Function
resistance to salicylic acid
Product
phenolic acid decarboxylase
Essential
no
Synonyms
bsdC, yclC
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0043 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
413,157 → 414,578
The protein
Catalyzed reaction/ biological activity
conversion of vanillic acid to guaiacol PubMed
4-hydroxybenzoate + H+ --> CO2 + phenol (according to UniProt)
4-hydroxy-3-methoxybenzoate + H+ --> CO2 + guaiacol (according to UniProt)
Protein family
ubiD family (single memberm, according to UniProt)
Structure
5M1B (PDB) (from E. coli, 31% identity) PubMed
P94405 (AlphaFold)
Expression and Regulation
Operons
Genes
bsdB-bsdC-bsdD
Description
PubMed
Regulation
induced by salicylic acid (BsdA) PubMed
Regulatory mechanism
BsdA: activation, PubMed, in bsdA regulon
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bsdB→bsdD

2025-03-08 15:30:24

ghost

64

9f1e53008322fc32f81f47f08c6a481f6a94f79a

5719B832927C879CFFE0ADDE90617DF8C801D919

Biological materials
Mutant
MGNA-C062 (yclC::erm), available at the NBRP B. subtilis, Japan
BKE03640 (ΔbsdC::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TCTGAAATCTTGATAAGCCA,  downstream forward: _UP4_AATAAATAAGGAAAGGATGT
BKK03640 (ΔbsdC::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TCTGAAATCTTGATAAGCCA,  downstream forward: _UP4_AATAAATAAGGAAAGGATGT
References
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Time of last update: 2025-03-30 19:18:04

Author of last update: Melvin.boenninger