bltD

bltD
168

spermidine/ spermine acetyltransferase

Locus
BSU_26600
Molecular weight
17.70 kDa
Isoelectric point
6.09
Protein length
152 aaSequenceBlast
Gene length
459 bpSequenceBlast
Function
spermidine degradation
Product
spermidine/ spermine acetyltransferase
Essential
no
E.C.
2.3.1.57
Synonyms
bltD, bmr2D, bmtD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1670 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,718,344  2,718,802
The protein
Catalyzed reaction/ biological activity
acetyl-CoA + an alkane-α,ω-diamine --> N-acetylalkane-α,ω-diamine + CoA + H+ (according to UniProt)
Domains
N-acetyltransferase domain (aa 3-152) (according to UniProt)
Structure
2FL4 (PDB) (from Enterococcus faecalis, 45% identity)
P39909 (AlphaFold)
Expression and Regulation
Operons
Genes
blt-bltD
Description
PubMed
Regulation
induced in the presence of polyamines PubMed
Regulatory mechanism
BltR: activation, PubMed, in bltR regulon
Mta: activation, PubMed, in mta regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
Open in new tab

blt→bltD

2025-03-21 22:06:28

Jstuelk

63

b4e14f59f67f753906676c35d6da7a84c76530fe

5ECA49F633CB14DCBAC061B7263474048BA8E727

Biological materials
Mutant
MGNA-C455 (bltD::erm), available at the NBRP B. subtilis, Japan
BKE26600 (bltD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACTACATTCTCCTTTTT,  downstream forward: _UP4_TAGATATCCAAGCCTCCTTG
BKK26600 (bltD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATACTACATTCTCCTTTTT,  downstream forward: _UP4_TAGATATCCAAGCCTCCTTG
References
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34360353D4488F1081FEF9A3CF8F1866D271657D

Page visits: 3379

Time of last update: 2025-03-30 04:27:41

Author of last update: Melvin.boenninger