bceR

bceR
168

two-component response regulator (OmpR family), regulation of bceA-bceB in response to external (bacitracin, plectasin, mersacidin and actagardine) and internal (SdpC, SkfA) antimicrobial peptides

Locus
BSU_30400
Molecular weight
26.72 kDa
Isoelectric point
5.29
Protein length
231 aaSequenceBlast
Gene length
696 bpSequenceBlast
Function
resistance against toxic peptides
Product
two-component response regulator (OmpR family)
Essential
no
Synonyms
bceR, ytsA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0745 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,113,187 → 3,113,882
The protein
Protein family
OmpR family
Domains
Response regulatory domain (aa 3-116) (according to UniProt)
Structure
1KGS (PDB) (DrrD from Thermotoga maritima , 32% identity) PubMed
O34951 (AlphaFold)
Modification
phosphorylated by BceS on an Asp residue
Localization
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
Genes
bceR-bceS
Description
PubMed
Open in new tab

bceR→bceS

2025-03-05 04:47:30

ghost

79

0d9c5f5aba9cd37b65e502c54a394ddb9aea0053

3ED24B86B015CF9A9605EB84290EFCB74C536FCF

Biological materials
Mutant
GP3218 Δ(bceR-bceS-bceA-bceB)::cat, available in Jörg Stülke's lab
MGNA-A133 (ytsA::erm), available at the NBRP B. subtilis, Japan
BKE30400 (ΔbceR::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATCGACTCACCGCACTTT,  downstream forward: _UP4_ATCGCGAAGGAAGAGGACAA
BKK30400 (ΔbceR::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATCGACTCACCGCACTTT,  downstream forward: _UP4_ATCGCGAAGGAAGAGGACAA
References
Reviews
Loading
Original Publications
Loading

C239C155F5452C86BF6C78190BABBBB07A63DF87

Page visits: 8296

Time of last update: 2025-04-03 14:37:33

Author of last update: Jstuelk