vpr

vpr
168

minor extracellular serine protease

Locus
BSU_38090
Molecular weight
85.42 kDa
Isoelectric point
5.77
Protein length
806 aaSequenceBlast
Gene length
2421 bpSequenceBlast
Function
protein degradation
Product
minor extracellular serine protease
Essential
no
Synonyms
vpr, ipa-45r
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1404 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,907,844  3,910,264
The protein
Protein family
peptidase S8 family (according to UniProt)
Domains
Inhibitor I9 domain (aa 57-142) (according to UniProt)
Peptidase S8 domain (aa 158-579) (according to UniProt)
Structure
P29141 (AlphaFold)
Localization
extracellular (signal peptide) PubMed
forms enzymatically active fibrils outside the cell PubMed
Expression and Regulation
Operons
Genes
vpr
Description
PubMed
Regulation
expressed under conditions of phosphate limitation (PhoP) PubMed
Regulatory mechanism
CodY: repression, PubMed, in codY regulon
PhoP: activation, PubMed, in phoP regulon
LexA: repression, PubMed, in lexA regulon
DnaA: repression, PubMed, in dnaA regulon
Sigma factors
SigH: sigma factor, PubMed, in sigH regulon
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vpr

2025-03-09 17:53:03

ghost

73

716795611eb699fcb1966c2eecfdde9177961236

C9DD489EBFD37E6E87D9A26F88E98B4BA92AE3BD

Biological materials
Mutant
KO7 (nprE  aprE  epr  mpr  nprB  vpr  bpr), available as BGSC 1A1133
BKE38090 (vpr::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATGTGTTTCCCCCTTTGT,  downstream forward: _UP4_TAAGAAAAAGCCCTGCCGAT
BKK38090 (vpr::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CAATGTGTTTCCCCCTTTGT,  downstream forward: _UP4_TAAGAAAAAGCCCTGCCGAT
References
Reviews
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Original Publications
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481AF959FDED9055F33524483101DA9AF2013151

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Time of last update: 2025-04-03 04:57:56

Author of last update: Jstuelk