oatA

oatA
168

O-acetyl transferase, provides resistance to lysozyme

Locus
BSU_27140
Molecular weight
72.04 kDa
Isoelectric point
9.45
Protein length
634 aaSequenceBlast
Gene length
1905 bpSequenceBlast
Function
resistance to lysozyme
Product
O-acetyl transferase
Essential
no
Synonyms
oatA, yrhL
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1835 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,771,318 → 2,773,222
Phenotypes of a mutant
increased sensitivity to lysozyme PubMed
The protein
Protein family
Acyltransferase 3 family (with YfiQ and YkrP, according to UniProt)
Structure
6VJP (PDB) (from Staphylococcus aureus, C-terminal extracytoplasmic domain) PubMed
O05402 (AlphaFold)
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
sigV-rsiV-oatA-yrhK
Description
PubMed
Regulation
induced by lysozyme (SigV) PubMed
Sigma factors
SigV: sigma factor, PubMed, in sigV regulon
Additional information
A ncRNA (RnaC) is encoded between 'yrhK' and 'yrhJ' PubMed
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sigV→yrhK

2025-04-03 10:09:15

ghost

136

615f2fda44a94485d48484b2f1ca14b4c127fd7e

083DE19EDE6E0BC14CEE435D7EC2FFBFBF00CE42

Biological materials
Mutant
MGNA-A146 (yrhL::erm), available at the NBRP B. subtilis, Japan
BKE27140 (ΔoatA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGGGTATTCCTCCAATAG,  downstream forward: _UP4_TAAAAAAGAGATCCTATACA
BKK27140 (ΔoatA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGGGTATTCCTCCAATAG,  downstream forward: _UP4_TAAAAAAGAGATCCTATACA
References
Research papers
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E97C7A219DB059BB634E893CC355A28324C87ADB

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Time of last update: 2025-04-08 12:09:33

Author of last update: Jstuelk