ribT

ribT
168

GCN5-like acetyltransferase (GNAT), acetylates RibH on K29

Locus
BSU_23240
Molecular weight
14.43 kDa
Isoelectric point
5.75
Protein length
124 aaSequenceBlast
Gene length
375 bpSequenceBlast
Function
acetylation of RibH
Product
RibH acetyltransferase
Essential
no
Synonyms
ribT, ribD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0456 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,427,405  2,427,779
The protein
Catalyzed reaction/ biological activity
acetylates RibH on K29 PubMed
Domains
N-acetyltransferase domain (aa 3-124) (according to UniProt)
Structure
5XXS (PDB) PubMed
P17622 (AlphaFold)
Localization
cytoplasm PubMed
Expression and Regulation
Operons
Genes
ribD-ribE-ribA-ribH-ribT
Description
PubMed
Regulation
expressed in the absence of FMN (FMN-box) PubMed
binding of RibR to the FMN-box riboswitch can enforce expression even in the presence of FMN PubMed
the FMN-box RNA is degraded by RNase Y PubMed
Regulatory mechanism
FMN-box: RNA switch, via FMN-box in the presence of FMN or FMNH2, this is counter-acted upon binding of RibR, in FMN-box
RibR: antitermination, PubMed, in ribR regulon
Sigma factors
SigA: sigma factor, PubMed, in sigA regulon
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ribD→ribT

2025-04-07 13:39:03

Jstuelk

123

3D660447137821317811200D29A5FC04A41E938E

05C8A4E892E7DB3D953FE72E8765638644759326

Biological materials
Mutant
BKE23240 (ribT::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAAAAACCCCTCTATATC,  downstream forward: _UP4_TAAGCAGAGGCTGTGATCAG
BKK23240 (ribT::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATAAAAACCCCTCTATATC,  downstream forward: _UP4_TAAGCAGAGGCTGTGATCAG
References
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Time of last update: 2025-04-08 06:15:12

Author of last update: Jstuelk