sco

sco
168

accessory lipoprotein required for assembly of the Cu(A) center of Cytochrome c oxidase caa3

Locus
BSU_21750
Molecular weight
21.50 kDa
Isoelectric point
4.81
Protein length
193 aaSequenceBlast
Gene length
582 bpSequenceBlast
Function
maturation of Cytochrome c oxidase caa3
Product
synthesis of cytochrome oxidase protein
Essential
no
Synonyms
sco, ypmQ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1999 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,291,703  2,292,284
The protein
Catalyzed reaction/ biological activity
electron transfer to the maturing oxidase Cytochrome c oxidase caa3 PubMed
Protein family
SCO1/2 family (single member, according to UniProt)
Domains
Thioredoxin domain (aa 26-191) (according to UniProt)
Cofactors
contains copper bound by two cysteines and a histidine residue PubMed
Structure
1XZO (PDB) PubMed
P54178 (AlphaFold)
Localization
lipoprotein, cell membrane  PubMed
Expression and Regulation
Operons
Genes
sco-ypmR-ypmS-ypmT
Description
PubMed
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sco→ypmT

2025-03-02 00:55:12

Jstuelk

97

d6ed3f20fd38bd7de55cce984764b26af8247cef

00F66E27C368E90AECAEFEEDCBB05239029A914C

Biological materials
Mutant
MGNA-A882 (ypmQ::erm), available at the NBRP B. subtilis, Japan
BKE21750 (sco::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGACATCCATCCTTTCCA,  downstream forward: _UP4_TAAGCTAAGAGACTAGGCAT
BKK21750 (sco::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATGACATCCATCCTTTCCA,  downstream forward: _UP4_TAAGCTAAGAGACTAGGCAT
Reviews
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References
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0337C7B1CFA1C59710A7E6463A370F8C39AAC8EA

Page visits: 2860

Time of last update: 2025-04-03 16:26:44

Author of last update: Jstuelk