Adk
- Description: adenylate kinase
| Gene name | adk |
| Synonyms | |
| Essential | yes PubMed |
| Product | adenylate kinase |
| Function | ADP formation |
| MW, pI | 23 kDa, 4.449 |
| Gene length, protein length | 651 bp, 217 aa |
| Immediate neighbours | secY, map |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU01370
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + AMP = 2 ADP (according to Swiss-Prot)
- Protein family: adenylate kinase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure: 1P3J
- Swiss prot entry: P16304
- KEGG entry: [2]
- E.C. number: 2.7.4.3 2.7.4.3]
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Rafael Couñago, Corey J Wilson, Matthew I Peña, Pernilla Wittung-Stafshede, Yousif Shamoo
An adaptive mutation in adenylate kinase that increases organismal fitness is linked to stability-activity trade-offs.
Protein Eng Des Sel: 2008, 21(1);19-27
[PubMed:18093993]
[WorldCat.org]
[DOI]
(P p)
J W Suh, S A Boylan, S H Oh, C W Price
Genetic and transcriptional organization of the Bacillus subtilis spc-alpha region.
Gene: 1996, 169(1);17-23
[PubMed:8635744]
[WorldCat.org]
[DOI]
(P p)
