XylB

• Description: xylulokinase
  
  

Gene name	xylB
Synonyms	yncA
Essential	no
Product	xylulokinase
Function	utilization of xylan and xylose
Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism
MW, pI	55 kDa, 6.459
Gene length, protein length	1497 bp, 499 aa
Immediate neighbours	xylA, yncB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU17610

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: ATP + D-xylulose = ADP + D-xylulose 5-phosphate (according to Swiss-Prot)

• Protein family: FGGY kinase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: P39211

• KEGG entry: [3]

• E.C. number: 2.7.1.17

Expression and regulation

• Operon: xylA-xylB

• Sigma factor: SigA

• Regulation: repressed by glucose (CcpA) , carbon catabolite repression (CcpA), induction by xylose (XylR)

• Regulatory mechanism: CcpA: transcription repression, CcpA: transcription repression, XylR: transcription repression

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Wolfgang Hillen, Erlangen University, Germany Homepage