GbsA
- Description: glycine betaine-aldehyde dehydrogenase, glycine betaine synthesis
Gene name | gbsA |
Synonyms | |
Essential | no |
Product | glycine betaine-aldehyde dehydrogenase |
Function | osmoprotection |
Metabolic function and regulation of this protein in SubtiPathways: Stress | |
MW, pI | 53 kDa, 4.713 |
Gene length, protein length | 1470 bp, 490 aa |
Immediate neighbours | gbsB, yuaC |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU31060
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Betaine aldehyde + NAD+ + H2O = betaine + NADH (according to Swiss-Prot)
- Protein family: aldehyde dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P71016
- KEGG entry: [2]
- E.C. number: 1.2.1.8
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Erhard Bremer, University of Marburg, Germany homepage
Your additional remarks
References
- Boch J, Nau-Wagner G, Kneip S, Bremer E. (1997) Glycine betaine aldehyde dehydrogenase from Bacillus subtilis: characterization of an enzyme required for the synthesis of the osmoprotectant glycine betaine. Arch Microbiol. Oct;168(4): 282-9. PubMed