GuaD
- Description: guanine deaminase, general stress protein
Gene name | guaD |
Synonyms | gde, yknA |
Essential | no |
Product | guanine deaminase |
Function | deamination of guanine to xanthine, purine salvage and interconversion |
MW, pI | 17 kDa, 4.999 |
Gene length, protein length | 468 bp, 156 aa |
Immediate neighbours | ohrB, metE |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU13170
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Guanine + H2O = xanthine + NH3 (according to Swiss-Prot)
- Protein family: cytidine and deoxycytidylate deaminase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure: 1WKQ
- Swiss prot entry: O34598
- KEGG entry: [3]
- E.C. number: 3.5.4.3
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528]
[WorldCat.org]
[DOI]
(P p)