CopZ

• Description: copper transport protein, metallochaperone
  
  

Gene name	copZ
Synonyms	yvgY
Essential	no
Product	copper transport protein, metallochaperone
Function	resistance to copper
MW, pI	7 kDa, 4.162
Gene length, protein length	207 bp, 69 aa
Immediate neighbours	copA, csoR
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: CopA-CopZ

• Localization: cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 2QIF

• Swiss prot entry: O32221

• KEGG entry: BSU33510

• E.C. number:

Expression and regulation

• Operon: copZ-copA PubMed

• Sigma factor: SigA PubMed

• Regulation: induced by copper PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

References

Agustina Rodriguez-Granillo, Pernilla Wittung-Stafshede
Tuning of copper-loop flexibility in Bacillus subtilis CopZ copper chaperone: role of conserved residues.
J Phys Chem B: 2009, 113(7);1919-32
[PubMed:19170606] [WorldCat.org] [DOI] (P p)

1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed