PdxT

• Description: pyridoxal-5�-phosphate synthase (glutaminase domain)
  
  

Gene name	pdxT
Synonyms	yaaE
Essential	no
Product	pyridoxal-5�-phosphate synthase (glutaminase domain)
Function	pyridoxal-5�-phosphate biosynthesis
MW, pI	21 kDa, 4.984
Gene length, protein length	588 bp, 196 aa
Immediate neighbours	pdxS, serS
Gene sequence (+200bp)	Protein sequence
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: PdxS-PdxT PubMed1 PubMed2

• Localization:

Database entries

• Structure: PdxT 2NV0, PdxS-PdxT complex 2NV2

• Swiss prot entry:

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: pdxS-pdxT

• Sigma factor:

• Regulation: negatively controlled by Spo0A PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Molle et al. (2003) The Spo0A regulon of Bacillus subtilis.Mol. Microbiol. 50: 1683-1701. PubMed
2. Raschle et al. (2005) On the two components of pyridoxal 5'-phosphate synthase from Bacillus subtilis.J. Biol. Chem. 280: 32291-32300. PubMed
3. Belitsky (2004) Physical and enzymological interaction of Bacillus subtilis proteins required for de novo pyridoxal 5'-phosphate biosynthesis.J. Bacteriol. 186: 1191-1196. PubMed