CheV

From SubtiWiki
Revision as of 14:55, 8 May 2015 by Jstuelk (talk | contribs)
Jump to: navigation, search
  • Description: modulation of CheA activity in response to attractants

Gene name cheV
Synonyms
Essential no
Product CheA modulator
Function control of CheA activity
Gene expression levels in SubtiExpress: cheV
Interactions involving this protein in SubtInteract: CheV
MW, pI 34 kDa, 4.617
Gene length, protein length 909 bp, 303 aa
Immediate neighbours ykzT, kre
Sequences Protein DNA DNA_with_flanks
Genetic context
CheV context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CheV expression.png















Categories containing this gene/protein

transcription factors and their control, phosphoproteins, motility and chemotaxis

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

  • Locus tag: BSU14010

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): CheW (N-terminal domain of CheV)

Extended information on the protein

  • Kinetic information:
  • Domains: N-terminal CheW-like domain, C-terminal two-component receiver domain PubMed
  • Modification: the C-terminal two-component receiver domain is phosphorylated on a Asp residue by CheA PubMed
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • forms lateral clusters (phosphorylated form), but in the presence of high asparagine concentration (non-phosphorylated form) there is a reversible re-localization to the poles of the cell PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • in minimal medium, CheV is present with 7,500 +/- 2,000 molecules per cell PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 1117 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 1764 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications