yitD

yitD
168

phosphosulfolactate synthase

Locus
BSU_10950
Molecular weight
28.21 kDa
Isoelectric point
4.38
Protein length
252 aaSequenceBlast
Gene length
759 bpSequenceBlast
Function
biosynthesis of L-sulfolactate
Product
phosphosulfolactate synthase
Essential
no
E.C.
4.4.1.19
Synonyms
yitD
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1809 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,173,333  1,174,091
The protein
Catalyzed reaction/ biological activity
H+ + phosphoenolpyruvate + sulfite --> (2R)-O-phospho-3-sulfolactate (according to UniProt)
Protein family
phosphosulfolactate synthase family (single member, according to UniProt)
Structure
1U83 (PDB)
O06739 (AlphaFold)
Expression and Regulation
Operons
Genes
yitC-yitD
Description
PubMed
Regulation
expressed during sporulation in the mother cell (SigE, SigK) PubMed
Sigma factors
SigE: sigma factor, PubMed, in sigE regulon
SigK: sigma factor, PubMed, in sigK regulon
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yitC→yitD

2025-04-03 23:20:04

ghost

64

ad2c7d1e628ef8018acb407596e904e7227b3b19

88CAA5C4794C71F1F27E2409BD1A24A4FE274C55

Biological materials
Mutant
MGNA-B178 (yitD::erm), available at the NBRP B. subtilis, Japan
BKE10950 (yitD::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGGCAATTCTAGTGAAAAAT,  downstream forward: _UP4_TAAAATAGCGGCTGCGGGGC
BKK10950 (yitD::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_TGGCAATTCTAGTGAAAAAT,  downstream forward: _UP4_TAAAATAGCGGCTGCGGGGC
References
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97156E7227E298B0DECC9AAC1411D0DAF3420C29

Page visits: 2110

Time of last update: 2025-04-08 14:04:44

Author of last update: Jstuelk