CzrA
- Description: transcriptional repressor (ArsR family), cadA and czcD
Gene name | czrA |
Synonyms | yozA |
Essential | no |
Product | transcriptional repressor (ArsR family) |
Function | regulation of resistance against toxic metal cations |
Gene expression levels in SubtiExpress: czrA | |
Metabolic function and regulation of this protein in SubtiPathways: metal ion homeostasis | |
MW, pI | 12 kDa, 5.719 |
Gene length, protein length | 321 bp, 107 aa |
Immediate neighbours | yobW, yocA |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
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Expression at a glance PubMed |
Contents
Categories containing this gene/protein
trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), transcription factors and their control, resistance against toxic metals
This gene is a member of the following regulons
The CzrA regulon:
The gene
Basic information
- Locus tag: BSU19120
Phenotypes of a mutant
Database entries
- BsubCyc: BSU19120
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: ArsR family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- DNA-binding activity of CzrA is inactivated by high concentrations of toxic metal ions (induction)
Database entries
- BsubCyc: BSU19120
- Structure:
- UniProt: O31844
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References