PgcM

• Description: β-phosphoglucomutase/ glucose-1-phosphate phosphodismutase
  
  

Gene name	pgcM
Synonyms	yvdM
Essential	no
Product	beta-phosphoglucomutase (EC 5.4.2.6 and EC 2.7.1.41)
Function	starch and maltodextrin utilization
Gene expression levels in SubtiExpress: pgcM
Metabolic function and regulation of this protein in SubtiPathways: pgcM
MW, pI	24 kDa, 4.76
Gene length, protein length	678 bp, 226 aa
Immediate neighbours	clpP, malL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources

The gene

Basic information

• Locus tag: BSU34550

Database entries

• BsubCyc: BSU34550

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Beta-D-glucose 1-phosphate = beta-D-glucose 6-phosphate (according to Swiss-Prot)

• Protein family: CbbY/cbbZ/gph/yieH family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU34550

• Structure: 3NAS; 1ZOL (from Lactococcus lactis, 48% identity, 66% similarity) PubMed

• UniProt: O06995

• KEGG entry: [2]

• E.C. number: 5.4.2.6

Expression and regulation

• Operon: yvdE-yvdF-mdxE-mdxF-mdxG-yvdJ-yvdK-malL-pgcM PubMed

• Expression browser: pgcM PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Stefan Schönert, Sabine Seitz, Holger Krafft, Eva-Anne Feuerbaum, Iris Andernach, Gabriele Witz, Michael K Dahl
Maltose and maltodextrin utilization by Bacillus subtilis.
J Bacteriol: 2006, 188(11);3911-22
[PubMed:16707683] [WorldCat.org] [DOI] (P p)

L R Mesak, M K Dahl
Purification and enzymatic characterization of PgcM: a beta-phosphoglucomutase and glucose-1-phosphate phosphodismutase of Bacillus subtilis.
Arch Microbiol: 2000, 174(4);256-64
[PubMed:11081794] [WorldCat.org] [DOI] (P p)