ywpB

ywpB
168

ß-hydroxyacyl-(acyl carrier protein) dehydratase

Locus
BSU_36370
Molecular weight
14.63 kDa
Isoelectric point
9.36
Protein length
141 aaSequenceBlast
Gene length
426 bpSequenceBlast
Function
fatty acid biosynthesis
Product
β-hydroxyacyl-ACP dehydratase
Essential
yes
E.C.
4.2.1.59
Synonyms
ywpB, fabZ
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0764 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,743,732 → 3,744,157
Phenotypes of a mutant
essential PubMed
The protein
Catalyzed reaction/ biological activity
(3R)-hydroxyacyl-[ACP] --> (2E)-enoyl-[ACP] + H2O (according to UniProt)
Protein family
thioester dehydratase family (with YcsD, according to UniProt)
Structure
3D6X (PDB) (from Campylobacter jejuni, 45% identity, 67% similarity) PubMed
P94584 (AlphaFold)
Paralogous protein(s)
YcsD
Expression and Regulation
Operons
Genes
ywpB-mscL
Description
PubMed
Regulation
expressed in logarithmic phase PubMed
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ywpB→mscL

2025-03-16 17:53:47

Jstuelk

112

5415340d20ac4baa52c66698ec0cc9bee9f29809

9C0AC698BF01AA86D7382CE0D746D52B12FABB4F

Biological materials
Mutant
MGNA-B265 (ywpB::erm), available at the NBRP B. subtilis, Japan
References
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BDA23FA513C240B07DC109BB62A7A5EB96B20965

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Time of last update: 2025-04-02 01:50:19

Author of last update: Jstuelk