LutA

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  • Description: lactate catabolic enzyme

Gene name lutA
Synonyms yvfV
Essential no
Product lactate oxidase
Function lactate utilization
Gene expression levels in SubtiExpress: lutA
Metabolic function and regulation of this protein in SubtiPathways:
lutA
MW, pI 26 kDa, 6.25
Gene length, protein length 714 bp, 238 aa
Immediate neighbours lutB, yvfU
Sequences Protein DNA DNA_with_flanks
Genetic context
YvfV context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LutA expression.png















Categories containing this gene/protein

utilization of specific carbon sources

This gene is a member of the following regulons

FbpB regulon, FsrA regulon, LutR regulon, SinR regulon

The gene

Basic information

  • Locus tag: BSU34050

Phenotypes of a mutant

no growth with lactate as the single carbon source PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: oxidation of lactate to pyruvate PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 289 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 2918 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 799 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 738 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 1342 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion: GP1612 amyE::p(lutA-lacZ cat), constructed with pGP2149 based on pAC5, available in Jörg Stülke's lab
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Richard Losick, Harvard Univ., Cambridge, USA homepage

Your additional remarks

References