NupO

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Gene name nupO
Synonyms yufO
Essential no
Product ABC transporter for guanosine
Function uptake of guanosine
Gene expression levels in SubtiExpress: nupO
Interactions involving this protein in SubtInteract: NupO
MW, pI 56 kDa, 7.497
Gene length, protein length 1530 bp, 510 aa
Immediate neighbours nupN, nupP
Sequences Protein DNA DNA_with_flanks
Genetic context
YufO context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NupO expression.png
























Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of nucleotides, membrane proteins

This gene is a member of the following regulons

CodY regulon

The gene

Basic information

  • Locus tag: BSU31550

Phenotypes of a mutant

  • a nupO nupG double mutant is unable to utilize externally provided guanosine PubMed

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium, exponential phase): 1042 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, early stationary phase after glucose exhaustion): 504 PubMed
    • number of protein molecules per cell (minimal medium with glucose and ammonium, late stationary phase after glucose exhaustion): 562 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References