GpsA

• Description: glycerol-3-phosphate dehydrogenase (NAD)
  
  

Gene name	gpsA
Synonyms
Essential	yes PubMed
Product	glycerol-3-phosphate dehydrogenase (NAD)
Function	biosynthesis of phospholipids
Gene expression levels in SubtiExpress: gpsA
Metabolic function and regulation of this protein in SubtiPathways: gpsA
MW, pI	37 kDa, 6.231
Gene length, protein length	1035 bp, 345 aa
Immediate neighbours	yphE, engA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of lipids, essential genes,

The gene

Basic information

• Locus tag: BSU22830

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU22830

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: sn-glycerol 3-phosphate + NAD(P)⁺ = glycerone phosphate + NAD(P)H (according to Swiss-Prot)

• Protein family: NAD-dependent glycerol-3-phosphate dehydrogenase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm PubMed

Database entries

• BsubCyc: BSU22830

• Structure: 3K96 (from Coxiella burnetii RSA 493, 37% identity, 59% similarity)

• UniProt: P46919

• KEGG entry: [2]

• E.C. number: 1.1.1.94

Expression and regulation

• Operon:

• Expression browser: gpsA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 165 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 809 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: