NrdEB

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  • Description: similar to ribonucleoside-diphosphate reductase (alpha subunit)

Gene name nrdEB
Synonyms yosN
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: nrdEB
MW, pI 27 kDa, 6.388
Gene length, protein length 3504 bp, 1084 aa
Immediate neighbours yosQ, yosM
Sequences Protein DNA DNA_with_flanks
Genetic context
YosN context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NrdEB expression.png
























Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides, SP-beta prophage

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU20060

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s): NrdE

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:
    • number of protein molecules per cell (minimal medium with glucose and ammonium): 167 PubMed
    • number of protein molecules per cell (complex medium with amino acids, without glucose): 463 PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Slavisa Stankovic, Blazenka Soldo, Tanja Beric-Bjedov, Jelena Knezevic-Vukcevic, Draga Simic, Vladimir Lazarevic
Subspecies-specific distribution of intervening sequences in the Bacillus subtilis prophage ribonucleotide reductase genes.
Syst Appl Microbiol: 2007, 30(1);8-15
[PubMed:16621400] [WorldCat.org] [DOI] (P p)

V Lazarevic
Ribonucleotide reductase genes of Bacillus prophages: a refuge to introns and intein coding sequences.
Nucleic Acids Res: 2001, 29(15);3212-8
[PubMed:11470879] [WorldCat.org] [DOI] (I p)

V Lazarevic, B Soldo, A Düsterhöft, H Hilbert, C Mauël, D Karamata
Introns and intein coding sequence in the ribonucleotide reductase genes of Bacillus subtilis temperate bacteriophage SPbeta.
Proc Natl Acad Sci U S A: 1998, 95(4);1692-7
[PubMed:9465078] [WorldCat.org] [DOI] (P p)