LepA

• Description: GTP-binding protein
  
  

Gene name	lepA
Synonyms	yqxB, yqeQ
Essential	no
Product	GTP-binding protein
Function	unknown
Gene expression levels in SubtiExpress: lepA
MW, pI	68 kDa, 4.984
Gene length, protein length	1836 bp, 612 aa
Immediate neighbours	hemN, yqxA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

GTP-binding proteins

The gene

Basic information

• Locus tag: BSU25510

Database entries

• BsubCyc: BSU25510

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LepA subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot), Cytoplasm (Homogeneous) PubMed

Database entries

• BsubCyc: BSU25510

• Structure:

• UniProt: P37949

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: lepA-hemN PubMed

• Expression browser: lepA PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 313 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 691 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

B Hippler, G Homuth, T Hoffmann, C Hungerer, W Schumann, D Jahn
Characterization of Bacillus subtilis hemN.
J Bacteriol: 1997, 179(22);7181-5
[PubMed:9371469] [WorldCat.org] [DOI] (P p)

G Homuth, M Heinemann, U Zuber, W Schumann
The genes of lepA and hemN form a bicistronic operon in Bacillus subtilis.
Microbiology (Reading): 1996, 142 ( Pt 7);1641-9
[PubMed:8757728] [WorldCat.org] [DOI] (P p)