SufA

• Description: iron-sulfur cluster scaffold protein
  
  

Gene name	sufA
Synonyms	yutM
Essential	no
Product	iron-sulfur cluster scaffold protein
Function	assembly of Fe-S clusters
Gene expression levels in SubtiExpress: sufA
Metabolic function and regulation of this protein in SubtiPathways: SufA
MW, pI	12 kDa, 4.52
Gene length, protein length	360 bp, 120 aa
Immediate neighbours	paiA, dapF
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

iron metabolism

The gene

Basic information

• Locus tag: BSU32160

Database entries

• BsubCyc: BSU32160

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: hesB/iscA family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU32160

• Structure: 1R94 (from E. coli) PubMed

• UniProt: O32113

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: sufA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 222 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 330 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Alexander G Albrecht, Daili J A Netz, Marcus Miethke, Antonio J Pierik, Olaf Burghaus, Florian Peuckert, Roland Lill, Mohamed A Marahiel
SufU is an essential iron-sulfur cluster scaffold protein in Bacillus subtilis.
J Bacteriol: 2010, 192(6);1643-51
[PubMed:20097860] [WorldCat.org] [DOI] (I p)

Patrick W Bilder, Huangen Ding, Marcia E Newcomer
Crystal structure of the ancient, Fe-S scaffold IscA reveals a novel protein fold.
Biochemistry: 2004, 43(1);133-9
[PubMed:14705938] [WorldCat.org] [DOI] (P p)