YodC

• Description: similar to nitroreductase
  
  

Gene name	yodC
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yodC
MW, pI	22 kDa, 5.274
Gene length, protein length	606 bp, 202 aa
Immediate neighbours	yodB, mhqD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

electron transport/ other, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

YodB regulon

The gene

Basic information

• Locus tag: BSU19550

Database entries

• BsubCyc: BSU19550

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: type A lantibiotic family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU19550

• Structure:

• UniProt: P81102

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yodC PubMed

• Sigma factor:

• Regulation:
  • induced by thiol-reactive compounds (catechol, menaquinone) (YodB) PubMed

• Regulatory mechanism:
  • YodB: transcription repression PubMed

• Additional information:
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 2680 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 1792 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Montira Leelakriangsak, Nguyen Thi Thu Huyen, Stefanie Töwe, Nguyen van Duy, Dörte Becher, Michael Hecker, Haike Antelmann, Peter Zuber
Regulation of quinone detoxification by the thiol stress sensing DUF24/MarR-like repressor, YodB in Bacillus subtilis.
Mol Microbiol: 2008, 67(5);1108-24
[PubMed:18208493] [WorldCat.org] [DOI] (I p)

Van Duy Nguyen, Carmen Wolf, Ulrike Mäder, Michael Lalk, Peter Langer, Ulrike Lindequist, Michael Hecker, Haike Antelmann
Transcriptome and proteome analyses in response to 2-methylhydroquinone and 6-brom-2-vinyl-chroman-4-on reveal different degradation systems involved in the catabolism of aromatic compounds in Bacillus subtilis.
Proteomics: 2007, 7(9);1391-408
[PubMed:17407181] [WorldCat.org] [DOI] (P p)