MoaA

• Description: molybdopterin precursor biosynthesis
  
  

Gene name	moaA
Synonyms	narA, narAB
Essential	no
Product	unknown
Function	nitrate respiration
Gene expression levels in SubtiExpress: moaA
Metabolic function and regulation of this protein in SubtiPathways: MoaA
MW, pI	38 kDa, 9.285
Gene length, protein length	1023 bp, 341 aa
Immediate neighbours	rapB, fdhD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors

The gene

Basic information

• Locus tag: BSU36700

Database entries

• BsubCyc: BSU36700

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • involved in the first step of molybdenum cofactor biosynthesis (together with YdiG)

• Protein family: MoaA family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors: contains an iron-sulfur cluster

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU36700

• Structure:

• UniProt: P39757

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: moaA PubMed

• Expression browser: moaA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Ralf R Mendel
The molybdenum cofactor.
J Biol Chem: 2013, 288(19);13165-72
[PubMed:23539623] [WorldCat.org] [DOI] (I p)

Original publications

M M Nakano, Y P Dailly, P Zuber, D P Clark
Characterization of anaerobic fermentative growth of Bacillus subtilis: identification of fermentation end products and genes required for growth.
J Bacteriol: 1997, 179(21);6749-55
[PubMed:9352926] [WorldCat.org] [DOI] (P p)

P Glaser, A Danchin, F Kunst, P Zuber, M M Nakano
Identification and isolation of a gene required for nitrate assimilation and anaerobic growth of Bacillus subtilis.
J Bacteriol: 1995, 177(4);1112-5
[PubMed:7860592] [WorldCat.org] [DOI] (P p)