SpeE

• Description: spermidine synthase
  
  

Gene name	speE
Synonyms	ywhF
Essential	no
Product	spermidine synthase
Function	spermidine, polyamine biosynthesis
Gene expression levels in SubtiExpress: speE
Metabolic function and regulation of this protein in SubtiPathways: speE
MW, pI	31 kDa, 5.068
Gene length, protein length	828 bp, 276 aa
Immediate neighbours	speB, pbpG
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

miscellaneous metabolic pathways

The gene

Basic information

• Locus tag: BSU37500

Database entries

• BsubCyc: BSU37500

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: S-adenosylmethioninamine + putrescine = 5'-S-methyl-5'-thioadenosine + spermidine (according to Swiss-Prot)

• Protein family: spermidine/spermine synthase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU37500

• Structure: 1IY9

• UniProt: P70998

• KEGG entry: [3]

• E.C. number: 2.5.1.16

Expression and regulation

• Operon:
  • speE-speB PubMed
  • speE PubMed

• Expression browser: speE PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

A Sekowska, P Bertin, A Danchin
Characterization of polyamine synthesis pathway in Bacillus subtilis 168.
Mol Microbiol: 1998, 29(3);851-8
[PubMed:9723923] [WorldCat.org] [DOI] (P p)