YvbW

• Description: putative leucine permease
  
  

Gene name	yvbW
Synonyms
Essential	no
Product	putative leucine permease
Function	unknown
Gene expression levels in SubtiExpress: yvbW
MW, pI	49 kDa, 9.837
Gene length, protein length	1341 bp, 447 aa
Immediate neighbours	yvbV, yvbX
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transporters/ other, membrane proteins

This gene is a member of the following regulons

T-box

The gene

Basic information

• Locus tag: BSU34010

Database entries

• BsubCyc: BSU34010

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:
  • secondary amino acid transporter
  • amino acid, polyamine, organocation (APC) superfamily of transporters, TC 2.A.3

• Paralogous protein(s): AapA, GabP, HutM, RocC, RocE, YbgF, YbxG, YdgF, YtnA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU34010

• Structure:

• UniProt: O32257

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yvbW PubMed

• Sigma factor:

• Regulation:
  • induced by leucine limitation (T-box) PubMed

• Regulatory mechanism:
  • T-box: RNA switch, transcriptional antitermination PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Michiel Wels, Tom Groot Kormelink, Michiel Kleerebezem, Roland J Siezen, Christof Francke
An in silico analysis of T-box regulated genes and T-box evolution in prokaryotes, with emphasis on prediction of substrate specificity of transporters.
BMC Genomics: 2008, 9;330
[PubMed:18625071] [WorldCat.org] [DOI] (I e)