YtxJ
- Description: general stress protein
Gene name | ytxJ |
Synonyms | csb40 |
Essential | no |
Product | unknown |
Function | unknown |
Gene expression levels in SubtiExpress: ytxJ | |
MW, pI | 12 kDa, 5.089 |
Gene length, protein length | 324 bp, 108 aa |
Immediate neighbours | aroA, ytxH |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
general stress proteins (controlled by SigB), phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU29760
Phenotypes of a mutant
Database entries
- BsubCyc: BSU29760
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: Trx family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: contains a single conserved Cys residue in a motif (TCPIS) reminiscent of that found in monothiol glutaredoxins [3]
- Modification: phosphorylation on (Thr-93 OR Ser-94 OR Ser-96 OR Thr-99) PubMed
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- BsubCyc: BSU29760
- Structure:
- UniProt: P39914
- KEGG entry: [4]
- E.C. number:
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
YpdA, YqiW, YphP and YtxJ cooccur in those species predicted to synthesize bacillithiol.
References
Ahmed Gaballa, Gerald L Newton, Haike Antelmann, Derek Parsonage, Heather Upton, Mamta Rawat, Al Claiborne, Robert C Fahey, John D Helmann
Biosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in Bacilli.
Proc Natl Acad Sci U S A: 2010, 107(14);6482-6
[PubMed:20308541]
[WorldCat.org]
[DOI]
(I p)
Boris Macek, Ivan Mijakovic, Jesper V Olsen, Florian Gnad, Chanchal Kumar, Peter R Jensen, Matthias Mann
The serine/threonine/tyrosine phosphoproteome of the model bacterium Bacillus subtilis.
Mol Cell Proteomics: 2007, 6(4);697-707
[PubMed:17218307]
[WorldCat.org]
[DOI]
(P p)
A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224]
[WorldCat.org]
[DOI]
(P p)
D Varón, M S Brody, C W Price
Bacillus subtilis operon under the dual control of the general stress transcription factor sigma B and the sporulation transcription factor sigma H.
Mol Microbiol: 1996, 20(2);339-50
[PubMed:8733232]
[WorldCat.org]
[DOI]
(P p)