CzcD

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  • Description: cation diffusion facilitator

Gene name czcD
Synonyms yrdO
Essential no
Product cation diffusion facilitator
Function cation efflux, resistence against Zn, Cu, Co, Ni
Gene expression levels in SubtiExpress: czcD
Metabolic function and regulation of this protein in SubtiPathways:
metal ion homeostasis
MW, pI 34 kDa, 5.859
Gene length, protein length 933 bp, 311 aa
Immediate neighbours trkA, yrdN
Sequences Protein DNA DNA_with_flanks
Genetic context
CzcD context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CzcD expression.png
























Categories containing this gene/protein

transporters/ other, trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), resistance against toxic metals, membrane proteins

This gene is a member of the following regulons

CzrA regulon

The gene

Basic information

  • Locus tag: BSU26650

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
    • induced in the presence of toxic metal ions (Zn(II), Cd(II), Co(II), Ni(II) and Cu(II)) (CzrA) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References