PapA

• Description: Xaa-Pro amino-peptidase
  
  

Gene name	papA
Synonyms	yqhT
Essential	no
Product	Xaa-Pro amino-peptidase
Function	degradation of proline-containing peptides
Gene expression levels in SubtiExpress: papA
Metabolic function and regulation of this protein in SubtiPathways: papA
MW, pI	37 kDa, 4.83
Gene length, protein length	1059 bp, 353 aa
Immediate neighbours	efp, yqhS
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of nitrogen sources other than amino acids, coping with hyper-osmotic stress

The gene

Basic information

• Locus tag: BSU24460

Database entries

• BsubCyc: BSU24460

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase M24B family (according to Swiss-Prot)

• Paralogous protein(s): PapB

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU24460

• Structure: 3Q6D (the B. anthracis enzyme, 65% identity, 82% similarity)

• UniProt: P54518

• KEGG entry: [2]

• E.C. number: 3.4.11.9

Expression and regulation

• Operon:

• Expression browser: papA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: available in the Erhard Bremer lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Erhard Bremer, Marburg University, Germany Homepage