BsaA

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  • Description: similar to glutathione peroxidase

Gene name bsaA
Synonyms
Essential no
Product unknown
Function unknown
Gene expression levels in SubtiExpress: bsaA
MW, pI 18 kDa, 5.251
Gene length, protein length 480 bp, 160 aa
Immediate neighbours ypgQ, metA
Sequences Protein DNA DNA_with_flanks
Genetic context
BsaA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
BsaA expression.png
























Categories containing this gene/protein

resistance against oxidative and electrophile stress

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU21900

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

The gene is annotated in KEGG as glutathione peroxidase EC 1.11.1.9. It is marked in Swiss-Prot as “glutathione peroxidase homolog” and in MetaCyc as “glutathione peroxidase”. Several studies suggested that glutathione is probably absent in B. subtilis. PubMed

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer, Dennis Vitkup
Automatic policing of biochemical annotations using genomic correlations.
Nat Chem Biol: 2010, 6(1);34-40
[PubMed:19935659] [WorldCat.org] [DOI] (I p)

V Capuano, N Galleron, P Pujic, A Sorokin, S D Ehrlich
Organization of the Bacillus subtilis 168 chromosome between kdg and the attachment site of the SP beta prophage: use of Long Accurate PCR and yeast artificial chromosomes for sequencing.
Microbiology (Reading): 1996, 142 ( Pt 11);3005-15
[PubMed:8969496] [WorldCat.org] [DOI] (P p)