YhaR

• Description: similar to enoyl CoA hydratase
  
  

Gene name	yhaR
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yhaR
MW, pI	27 kDa, 6.355
Gene length, protein length	765 bp, 255 aa
Immediate neighbours	khtS, yhzD
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

membrane proteins, poorly characterized/ putative enzymes, sporulation proteins

This gene is a member of the following regulons

CcpA regulon

The gene

Basic information

• Locus tag: BSU09880

Database entries

• BsubCyc: BSU09880

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: enoyl-CoA hydratase/isomerase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU09880

• Structure:

• UniProt: O07533

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: yhaR PubMed

• Sigma factor:

• Regulation: repressed by glucose (17-fold) (CcpA) PubMed

• Regulatory mechanism: CcpA: transcription repression

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Hans-Matti Blencke, Georg Homuth, Holger Ludwig, Ulrike Mäder, Michael Hecker, Jörg Stülke
Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways.
Metab Eng: 2003, 5(2);133-49
[PubMed:12850135] [WorldCat.org] [DOI] (P p)