natK

natK
168

two-component sensor kinase, regulation of the natA-natB operon

Locus
BSU_02730
Molecular weight
34.92 kDa
Isoelectric point
8.05
Protein length
318 aaSequenceBlast
Gene length
957 bpSequenceBlast
Function
regulation of the natA-natB operon
Product
two-component sensor kinase
Essential
no
Synonyms
natK, yccG
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG3290 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
294,615  295,571
The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of NatR in response to sodium availability
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)
Domains
three transmembrane segments
Histidine kinase domain (aa 132-318) (according to UniProt)
Structure
P70954 (AlphaFold)
Modification
autophosphorylation on a His residue
Localization
cell membrane (according to UniProt)
Expression and Regulation
Operons
Genes
natR-natK
Description
PubMed
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natR→natK

2025-04-07 06:19:16

Jstuelk

107

6033418d44d4ee934be10c40c9057897d0b92659

ACC0CCF7E3D9FD26556A01A19C0236CC1543064C

Biological materials
Mutant
MGNA-C042 (yccG::erm), available at the NBRP B. subtilis, Japan
BKE02730 (natK::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AAGGGTAATCACGTACTAAA,  downstream forward: _UP4_TAAAAAAACCTTGAAAAGCC
BKK02730 (natK::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_AAGGGTAATCACGTACTAAA,  downstream forward: _UP4_TAAAAAAACCTTGAAAAGCC
References
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Page visits: 4890

Time of last update: 2025-04-06 12:46:33

Author of last update: Melvin.boenninger